A collaboration with Filippo Mancia from Columbia University is poised to determine the structure of membrane enzymes crucial for drug design and the understanding of pathologies linked to metabolite transport and transformation.

A multinational and multidisciplinary effort suppoted by a MSCA RISE action, Prometeus-Rise Protein and Membrane Technology Consortium (https://prometeus-rise.org/), is coordinated by the Vallone Lab.

Main Publications

Subcellular localization of the five members of the human steroid 5α-reductase family.
Scaglione A, Montemiglio LC, Parisi G, Asteriti IA, Bruni R, Cerutti G, Testi C, Savino C, Mancia F, Lavia P, Vallone B.
Biochim Open. 2017 Jun;4:99-106. doi: 10.1016/j.biopen.2017.03.003. Epub 2017 Mar 21.
PMID: 29082129
Free PMC Article